👉 Stops engineering, also known as stop codon recognition or stop signal recognition, is a critical process in molecular biology where specific sequences of three nucleotides at the end of an mRNA molecule signal the termination of protein synthesis. These sequences—UAA, UAG, and UGA—are known as stop codons. During translation, when a ribosome encounters a stop codon, it recruits release factors that promote the hydrolysis of the bond between the polypeptide chain and the tRNA, effectively halting further protein elongation. This process ensures that proteins are synthesized to the correct length and prevents the production of potentially harmful truncated or misfolded proteins. Stops engineering is thus essential for accurate gene expression and proper cellular function.
